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GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model

The pathobiology of Parkinson's disease (PD) is associated with the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) projecting to the striatum. Currently, there are no treatments that can halt or reverse the course of PD; only palliative therapies, such as replacement...

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Detalles Bibliográficos
Autores principales: Zhao, Yuling, Haney, Matthew J., Gupta, Richa, Bohnsack, John P., He, Zhijian, Kabanov, Alexander V., Batrakova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167552/
https://www.ncbi.nlm.nih.gov/pubmed/25229627
http://dx.doi.org/10.1371/journal.pone.0106867