Cargando…
GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model
The pathobiology of Parkinson's disease (PD) is associated with the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) projecting to the striatum. Currently, there are no treatments that can halt or reverse the course of PD; only palliative therapies, such as replacement...
Autores principales: | Zhao, Yuling, Haney, Matthew J., Gupta, Richa, Bohnsack, John P., He, Zhijian, Kabanov, Alexander V., Batrakova, Elena V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167552/ https://www.ncbi.nlm.nih.gov/pubmed/25229627 http://dx.doi.org/10.1371/journal.pone.0106867 |
Ejemplares similares
-
Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease
por: Zhao, Yuling, et al.
Publicado: (2022) -
Extracellular Vesicles Released by Genetically Modified Macrophages Activate Autophagy and Produce Potent Neuroprotection in Mouse Model of Lysosomal Storage Disorder, Batten Disease
por: El-Hage, Nazira, et al.
Publicado: (2023) -
Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases
por: Haney, Matthew J., et al.
Publicado: (2013) -
Effects of striatal transplantation of cells transfected with GDNF gene without pre- and pro-regions in mouse model of Parkinson’s disease
por: Revishchin, A., et al.
Publicado: (2016) -
Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
por: Mahajan, Vivek, et al.
Publicado: (2016)