Cargando…

Crystal structure of a human GABA(A) receptor

Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABA(A)R signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Paul S., Aricescu, A. Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167603/
https://www.ncbi.nlm.nih.gov/pubmed/24909990
http://dx.doi.org/10.1038/nature13293