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Crystal structure of a human GABA(A) receptor

Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABA(A)R signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional...

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Detalles Bibliográficos
Autores principales:	Miller, Paul S., Aricescu, A. Radu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167603/ https://www.ncbi.nlm.nih.gov/pubmed/24909990 http://dx.doi.org/10.1038/nature13293

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