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A neuron-glia interaction involving GABA Transaminase contributes to sleep loss in sleepless mutants

Sleep is an essential process and yet mechanisms underlying it are not well understood. Loss of the Drosophila quiver/sleepless (qvr/sss) gene increases neuronal excitability and diminishes daily sleep, providing an excellent model for exploring the underpinnings of sleep regulation. Here, we used a...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Feng, Maguire, Sarah, Sowcik, Mallory, Luo, Wenyu, Koh, Kyunghee, Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168011/
https://www.ncbi.nlm.nih.gov/pubmed/24637426
http://dx.doi.org/10.1038/mp.2014.11