Twist1 expression induced by sunitinib accelerates tumor cell vasculogenic mimicry by increasing the population of CD133(+) cells in triple-negative breast cancer

BACKGROUND: Hypoxia induced by antiangiogenic agents is linked to the generation of cancer stem cells (CSCs) and treatment failure through unknown mechanisms. The generation of endothelial cell-independent microcirculation in malignant tumors is defined as tumor cell vasculogenic mimicry (VM). In th...

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Detalles Bibliográficos
Autores principales: Zhang, Danfang, Sun, Baocun, Zhao, Xiulan, Ma, Yuemei, Ji, Ru, Gu, Qiang, Dong, Xueyi, Li, Jing, Liu, Fang, Jia, Xiaohua, Leng, Xue, Zhang, Chong, Sun, Ran, Chi, Jiadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168051/
https://www.ncbi.nlm.nih.gov/pubmed/25200065
http://dx.doi.org/10.1186/1476-4598-13-207

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