Tax impairs DNA replication forks and increases DNA breaks in specific oncogenic genome regions

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-I) is a human retrovirus associated with adult T-cell leukemia (ATL), an aggressive CD4 T-cell proliferative disease with dismal prognosis. The long latency preceding the development of the disease and the low incidence suggests that the virus its...

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Detalles Bibliográficos
Autores principales: Chaib-Mezrag, Hassiba, Lemaçon, Delphine, Fontaine, Hélène, Bellon, Marcia, Bai, Xue Tao, Drac, Marjorie, Coquelle, Arnaud, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168069/
https://www.ncbi.nlm.nih.gov/pubmed/25185513
http://dx.doi.org/10.1186/1476-4598-13-205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168069/
https://www.ncbi.nlm.nih.gov/pubmed/25185513
http://dx.doi.org/10.1186/1476-4598-13-205

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