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Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3(+) regulatory T cells in humans and mice

Unlike induced Foxp3(+) regulatory T cells (Foxp3(+) iT(reg)) that have been shown to play an essential role in the development of protective immunity to the ubiquitous mold Aspergillus fumigatus, type-(1)-regulatory T cells (Tr1) cells have, thus far, not been implicated in this process. Here, we e...

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Detalles Bibliográficos
Autores principales: Bedke, Tanja, Iannitti, Rossana G, De Luca, Antonella, Giovannini, Gloria, Fallarino, Francesca, Berges, Carsten, Latgé, Jean-Paul, Einsele, Hermann, Romani, Luigina, Topp, Max S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168117/
https://www.ncbi.nlm.nih.gov/pubmed/24820384
http://dx.doi.org/10.1038/icb.2014.34