A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

BACKGROUND: Malaria is a devastating parasitic disease, causing more than 600,000 deaths annually. Drug resistance has rendered previous generation anti-malarials ineffective and is also rapidly emerging against the current therapeutics of choice, artemisinin and its derivatives, making the discover...

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Detalles Bibliográficos
Autores principales: Fletcher, Sabine, Avery, Vicky M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168161/
https://www.ncbi.nlm.nih.gov/pubmed/25174342
http://dx.doi.org/10.1186/1475-2875-13-343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168161/
https://www.ncbi.nlm.nih.gov/pubmed/25174342
http://dx.doi.org/10.1186/1475-2875-13-343

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