A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells

BACKGROUND: The 90-kDa heat shock protein HSP90AA1 is critical for the stability of several proteins that are important for tumor progression and thus, is a promising target for cancer therapy. Selenosemicarbazone metal complexes have been shown to possess anticancer activity through an unknown mole...

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Detalles Bibliográficos
Autores principales: Shen, Hongtao, Zhu, Haichuan, Song, Mowei, Tian, Yonglu, Huang, Yafei, Zheng, Hui, Cao, Ruiyuan, Lin, Jian, Bi, Zhenggang, Zhong, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168210/
https://www.ncbi.nlm.nih.gov/pubmed/25167922
http://dx.doi.org/10.1186/1471-2407-14-629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168210/
https://www.ncbi.nlm.nih.gov/pubmed/25167922
http://dx.doi.org/10.1186/1471-2407-14-629

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