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Anti-Tumor Effect of a Novel Soluble Recombinant Human Endostatin: Administered as a Single Agent or in Combination with Chemotherapy Agents in Mouse Tumor Models

BACKGROUND: Angiogenesis has become an attractive target in cancer treatment. Endostatin is one of the potent anti-angiogenesis agents. Its recombinant form expressed in the yeast system is currently under clinical trials. Endostatin suppresses tumor formation through the inhibition of blood vessel...

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Detalles Bibliográficos
Autores principales: Ren, Zhihua, Wang, Yanan, Jiang, Wenhong, Dai, Wei, Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168263/
https://www.ncbi.nlm.nih.gov/pubmed/25229620
http://dx.doi.org/10.1371/journal.pone.0107823