Epigenetic Mechanisms Underlying the Dynamic Expression of Cancer-Testis Genes, PAGE2, -2B and SPANX-B, during Mesenchymal-to-Epithelial Transition

Cancer-testis (CT) genes are expressed in various cancers but not in normal tissues other than in cells of the germline. Although DNA demethylation of promoter-proximal CpGs of CT genes is linked to their expression in cancer, the mechanisms leading to demethylation are unknown. To elucidate such me...

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Detalles Bibliográficos
Autores principales: Yilmaz-Ozcan, Sinem, Sade, Asli, Kucukkaraduman, Baris, Kaygusuz, Yasemin, Senses, Kerem Mert, Banerjee, Sreeparna, Gure, Ali Osmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168264/
https://www.ncbi.nlm.nih.gov/pubmed/25229454
http://dx.doi.org/10.1371/journal.pone.0107905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168264/
https://www.ncbi.nlm.nih.gov/pubmed/25229454
http://dx.doi.org/10.1371/journal.pone.0107905

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