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Serum Stable Natural Peptides Designed by mRNA Display

Peptides constructed with the 20 natural amino acids are generally considered to have little therapeutic potential because they are unstable in the presence of proteases and peptidases. However, proteolysis cleavage can be idiosyncratic, and it is possible that natural analogues of functional sequen...

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Detalles Bibliográficos
Autores principales: Howell, Shannon M., Fiacco, Stephen V., Takahashi, Terry T., Jalali-Yazdi, Farzad, Millward, Steven W., Hu, Biliang, Wang, Pin, Roberts, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168267/
https://www.ncbi.nlm.nih.gov/pubmed/25234472
http://dx.doi.org/10.1038/srep06008