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Serum Stable Natural Peptides Designed by mRNA Display
Peptides constructed with the 20 natural amino acids are generally considered to have little therapeutic potential because they are unstable in the presence of proteases and peptidases. However, proteolysis cleavage can be idiosyncratic, and it is possible that natural analogues of functional sequen...
Autores principales: | Howell, Shannon M., Fiacco, Stephen V., Takahashi, Terry T., Jalali-Yazdi, Farzad, Millward, Steven W., Hu, Biliang, Wang, Pin, Roberts, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168267/ https://www.ncbi.nlm.nih.gov/pubmed/25234472 http://dx.doi.org/10.1038/srep06008 |
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