Characterizing variability in warfarin dose requirements in children using modelling and simulation

AIMS: Although genetic, clinical and demographic factors have been shown to explain approximately half of the inter-individual variability in warfarin dose requirement in adults, less is known about causes of dose variability in children. This study aimed to identify and quantify major genetic, clin...

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Detalles Bibliográficos
Autores principales: Hamberg, Anna-Karin, Wadelius, Mia, Friberg, Lena E, Biss, Tina T, Kamali, Farhad, Jonsson, E Niclas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2014
Materias:
Paediatric Clinical Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168390/
https://www.ncbi.nlm.nih.gov/pubmed/24330000
http://dx.doi.org/10.1111/bcp.12308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168390/
https://www.ncbi.nlm.nih.gov/pubmed/24330000
http://dx.doi.org/10.1111/bcp.12308

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