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Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits

Genome-wide association studies have been successful in identifying common variants that impact complex human traits and diseases. However, despite this success, the joint effects of these variants explain only a small proportion of the genetic variance in these phenotypes, leading to speculation th...

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Detalles Bibliográficos
Autores principales: Moutsianas, Loukas, Morris, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168660/
https://www.ncbi.nlm.nih.gov/pubmed/24916163
http://dx.doi.org/10.1093/bfgp/elu012