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Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits
Genome-wide association studies have been successful in identifying common variants that impact complex human traits and diseases. However, despite this success, the joint effects of these variants explain only a small proportion of the genetic variance in these phenotypes, leading to speculation th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168660/ https://www.ncbi.nlm.nih.gov/pubmed/24916163 http://dx.doi.org/10.1093/bfgp/elu012 |