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Syntheses of (15)N-labeled pre-queuosine nucleobase derivatives

Pre-queuosine or queuine (preQ(1)) is a guanine derivative that is involved in the biosynthetic pathway of the hypermodified tRNA nucleoside queuosine (Que). The core structure of preQ(1) is represented by 7-(aminomethyl)-7-deazaguanine (preQ(1) base). Here, we report the synthesis of three preQ(1)...

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Detalles Bibliográficos
Autores principales: Levic, Jasmin, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168690/
https://www.ncbi.nlm.nih.gov/pubmed/25246950
http://dx.doi.org/10.3762/bjoc.10.199