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Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats

It has been well documented that β-amyloid (Aβ) peptide accumulation and aggregation in the brain plays a crucial role in the pathophysiology of Alzheimer’s disease (AD). However, a new orientation of the amyloid cascade hypothesis has evidenced that soluble forms of the peptide (sAβ) are involved i...

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Detalles Bibliográficos
Autores principales: Tucci, Paolo, Mhillaj, Emanuela, Morgese, Maria Grazia, Colaianna, Marilena, Zotti, Margherita, Schiavone, Stefania, Cicerale, Maria, Trezza, Viviana, Campolongo, Patrizia, Cuomo, Vincenzo, Trabace, Luigia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168698/
https://www.ncbi.nlm.nih.gov/pubmed/25285073
http://dx.doi.org/10.3389/fnbeh.2014.00332