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Near-optimal assembly for shotgun sequencing with noisy reads

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...

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Detalles Bibliográficos
Autores principales: Lam, Ka-Kit, Khalak, Asif, Tse, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168708/
https://www.ncbi.nlm.nih.gov/pubmed/25252708
http://dx.doi.org/10.1186/1471-2105-15-S9-S4