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Near-optimal assembly for shotgun sequencing with noisy reads
Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...
Autores principales: | Lam, Ka-Kit, Khalak, Asif, Tse, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168708/ https://www.ncbi.nlm.nih.gov/pubmed/25252708 http://dx.doi.org/10.1186/1471-2105-15-S9-S4 |
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