Cargando…

BADGE: A novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data

BACKGROUND: Recent advances in RNA sequencing (RNA-Seq) technology have offered unprecedented scope and resolution for transcriptome analysis. However, precise quantification of mRNA abundance and identification of differentially expressed genes are complicated due to biological and technical variat...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Jinghua, Wang, Xiao, Halakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168709/
https://www.ncbi.nlm.nih.gov/pubmed/25252852
http://dx.doi.org/10.1186/1471-2105-15-S9-S6