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BADGE: A novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data

BACKGROUND: Recent advances in RNA sequencing (RNA-Seq) technology have offered unprecedented scope and resolution for transcriptome analysis. However, precise quantification of mRNA abundance and identification of differentially expressed genes are complicated due to biological and technical variat...

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Detalles Bibliográficos
Autores principales: Gu, Jinghua, Wang, Xiao, Halakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168709/
https://www.ncbi.nlm.nih.gov/pubmed/25252852
http://dx.doi.org/10.1186/1471-2105-15-S9-S6

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