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Local membrane deformation and micro-injury lead to qualitatively different responses in osteoblasts

Micro-damage of bone tissue is known to regulate bone turnover. However, it is unknown if individual bone cells can differentiate between membrane deformation and micro-injury. We generated osteoblasts from mouse bone marrow or bone morphogenetic protein 2-transfected C2C12 cells. Single cells were...

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Detalles Bibliográficos
Autores principales: Lopez-Ayon, G. Monserratt, Liu, Heng-Yen, Xing, Shu, Maria, Osama M., LeDue, Jeffrey M., Bourque, Helene, Grutter, Peter, Komarova, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168753/
https://www.ncbi.nlm.nih.gov/pubmed/25254108
http://dx.doi.org/10.12688/f1000research.4448.1