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Local membrane deformation and micro-injury lead to qualitatively different responses in osteoblasts
Micro-damage of bone tissue is known to regulate bone turnover. However, it is unknown if individual bone cells can differentiate between membrane deformation and micro-injury. We generated osteoblasts from mouse bone marrow or bone morphogenetic protein 2-transfected C2C12 cells. Single cells were...
Autores principales: | Lopez-Ayon, G. Monserratt, Liu, Heng-Yen, Xing, Shu, Maria, Osama M., LeDue, Jeffrey M., Bourque, Helene, Grutter, Peter, Komarova, Svetlana V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168753/ https://www.ncbi.nlm.nih.gov/pubmed/25254108 http://dx.doi.org/10.12688/f1000research.4448.1 |
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