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Synthesis of Complex Hexacyclic Compounds via a Tandem Rh(II)-Catalyzed Double-Cyclopropanation/Cope Rearrangement/Diels–Alder Reaction
[Image: see text] Treatment of (E)-1-(methoxymethylene)-1,2,3,4-tetrahydronaphthalene with styryl diazoacetates in the presence of catalytic amounts of the dirhodium complex Rh(2)(S-DOSP)(4) provides a highly enantioenriched hexacyclic product with 10 new stereogenic centers. The transformation proc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168775/ https://www.ncbi.nlm.nih.gov/pubmed/25208337 http://dx.doi.org/10.1021/ol502257d |