Silyl Enol Ether Prins Cyclization: Diastereoselective Formation of Substituted Tetrahydropyran-4-ones

[Image: see text] A diastereoselective synthesis of cis-2,6-disubstituted tetrahydropyran-4-ones was developed. The key step of this methodology, a silyl enol ether Prins cyclization, was promoted by a condensation reaction between a hydroxy silyl enol ether and an aldehyde to afford substituted tet...

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Detalles Bibliográficos
Autores principales: Tay, Gidget C., Huang, Chloe Y., Rychnovsky, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168786/
https://www.ncbi.nlm.nih.gov/pubmed/25200563
http://dx.doi.org/10.1021/jo501580p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168786/
https://www.ncbi.nlm.nih.gov/pubmed/25200563
http://dx.doi.org/10.1021/jo501580p

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