Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

[Image: see text] 4′-Phosphopantetheinyl transferases (PPTase) post-translationally modify carrier proteins with a phosphopantetheine moiety, an essential reaction in all three domains of life. In the bacterial genus Mycobacteria, the Sfp-type PPTase activates pathways necessary for the biosynthesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Vickery, Christopher R., Kosa, Nicolas M., Casavant, Ellen P., Duan, Shiteng, Noel, Joseph P., Burkart, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168790/
https://www.ncbi.nlm.nih.gov/pubmed/24963544
http://dx.doi.org/10.1021/cb500263p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168790/
https://www.ncbi.nlm.nih.gov/pubmed/24963544
http://dx.doi.org/10.1021/cb500263p

Ejemplares similares