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Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

[Image: see text] 4′-Phosphopantetheinyl transferases (PPTase) post-translationally modify carrier proteins with a phosphopantetheine moiety, an essential reaction in all three domains of life. In the bacterial genus Mycobacteria, the Sfp-type PPTase activates pathways necessary for the biosynthesis...

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Detalles Bibliográficos
Autores principales:	Vickery, Christopher R., Kosa, Nicolas M., Casavant, Ellen P., Duan, Shiteng, Noel, Joseph P., Burkart, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168790/ https://www.ncbi.nlm.nih.gov/pubmed/24963544 http://dx.doi.org/10.1021/cb500263p

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