Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

[Image: see text] Inhibition of histone demethylases has within recent years advanced into a new strategy for treating cancer and other diseases. Targeting specific histone demethylases can be challenging, as the active sites of KDM1A-B and KDM4A-D histone demethylases are highly conserved. Most inh...

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Detalles Bibliográficos
Autores principales: Leurs, Ulrike, Lohse, Brian, Rand, Kasper D., Ming, Shonoi, Riise, Erik S., Cole, Philip A., Kristensen, Jesper L., Clausen, Rasmus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168794/
https://www.ncbi.nlm.nih.gov/pubmed/25014588
http://dx.doi.org/10.1021/cb500374f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168794/
https://www.ncbi.nlm.nih.gov/pubmed/25014588
http://dx.doi.org/10.1021/cb500374f

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