Cargando…

Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing

[Image: see text] Phosphorodiamidate morpholino oligonucleotides are widely used to interrogate gene function in whole organisms, and light-activatable derivatives can reveal spatial and temporal differences in gene activity. We describe here a new class of caged morpholino oligonucleotides that can...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamazoe, Sayumi, McQuade, Lindsey E., Chen, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168795/
https://www.ncbi.nlm.nih.gov/pubmed/25069083
http://dx.doi.org/10.1021/cb500429u