Nucleophilic 1,4-Additions for Natural Product Discovery

[Image: see text] Natural products remain an important source of drug candidates, but the difficulties inherent to traditional isolation, coupled with unacceptably high rates of compound rediscovery, limit the pace of natural product detection. Here we describe a reactivity-based screening method to...

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Detalles Bibliográficos
Autores principales: Cox, Courtney L., Tietz, Jonathan I., Sokolowski, Karol, Melby, Joel O., Doroghazi, James R., Mitchell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168802/
https://www.ncbi.nlm.nih.gov/pubmed/24937678
http://dx.doi.org/10.1021/cb500324n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168802/
https://www.ncbi.nlm.nih.gov/pubmed/24937678
http://dx.doi.org/10.1021/cb500324n

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