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Nucleophilic 1,4-Additions for Natural Product Discovery
[Image: see text] Natural products remain an important source of drug candidates, but the difficulties inherent to traditional isolation, coupled with unacceptably high rates of compound rediscovery, limit the pace of natural product detection. Here we describe a reactivity-based screening method to...
Autores principales: | Cox, Courtney L., Tietz, Jonathan I., Sokolowski, Karol, Melby, Joel O., Doroghazi, James R., Mitchell, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168802/ https://www.ncbi.nlm.nih.gov/pubmed/24937678 http://dx.doi.org/10.1021/cb500324n |
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