Biodegradable drug-eluting nanofiber-enveloped implants for sustained release of high bactericidal concentrations of vancomycin and ceftazidime: in vitro and in vivo studies

We developed biodegradable drug-eluting nanofiber-enveloped implants that provided sustained release of vancomycin and ceftazidime. To prepare the biodegradable nanofibrous membranes, poly(D,L)-lactide-co-glycolide and the antibiotics were first dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol. They w...

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Detalles Bibliográficos
Autores principales: Hsu, Yung-Heng, Chen, Dave Wei-Chih, Tai, Chun-Der, Chou, Ying-Chao, Liu, Shih-Jung, Ueng, Steve Wen-Neng, Chan, Err-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168873/
https://www.ncbi.nlm.nih.gov/pubmed/25246790
http://dx.doi.org/10.2147/IJN.S66526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168873/
https://www.ncbi.nlm.nih.gov/pubmed/25246790
http://dx.doi.org/10.2147/IJN.S66526

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