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Expeditive synthesis of trithiotriazine-cored glycoclusters and inhibition of Pseudomonas aeruginosa biofilm formation

Readily accessible, low-valency glycoclusters based on a triazine core bearing D-galactose and L-fucose epitopes are able to inhibit biofilm formation by Pseudomonas aeruginosa. These multivalent ligands are simple to synthesize, are highly soluble, and can be either homofunctional or heterofunction...

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Detalles Bibliográficos
Autores principales: Smadhi, Meriem, de Bentzmann, Sophie, Imberty, Anne, Gingras, Marc, Abderrahim, Raoudha, Goekjian, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168900/
https://www.ncbi.nlm.nih.gov/pubmed/25246957
http://dx.doi.org/10.3762/bjoc.10.206