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eMatchSite: Sequence Order-Independent Structure Alignments of Ligand Binding Pockets in Protein Models

Detecting similarities between ligand binding sites in the absence of global homology between target proteins has been recognized as one of the critical components of modern drug discovery. Local binding site alignments can be constructed using sequence order-independent techniques, however, to achi...

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Detalles Bibliográficos
Autor principal: Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168975/
https://www.ncbi.nlm.nih.gov/pubmed/25232727
http://dx.doi.org/10.1371/journal.pcbi.1003829