A Systems Approach to Predict Oncometabolites via Context-Specific Genome-Scale Metabolic Networks

Altered metabolism in cancer cells has been viewed as a passive response required for a malignant transformation. However, this view has changed through the recently described metabolic oncogenic factors: mutated isocitrate dehydrogenases (IDH), succinate dehydrogenase (SDH), and fumarate hydratase...

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Detalles Bibliográficos
Autores principales: Nam, Hojung, Campodonico, Miguel, Bordbar, Aarash, Hyduke, Daniel R., Kim, Sangwoo, Zielinski, Daniel C., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168981/
https://www.ncbi.nlm.nih.gov/pubmed/25232952
http://dx.doi.org/10.1371/journal.pcbi.1003837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168981/
https://www.ncbi.nlm.nih.gov/pubmed/25232952
http://dx.doi.org/10.1371/journal.pcbi.1003837

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