Cargando…
A Systems Approach to Predict Oncometabolites via Context-Specific Genome-Scale Metabolic Networks
Altered metabolism in cancer cells has been viewed as a passive response required for a malignant transformation. However, this view has changed through the recently described metabolic oncogenic factors: mutated isocitrate dehydrogenases (IDH), succinate dehydrogenase (SDH), and fumarate hydratase...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168981/ https://www.ncbi.nlm.nih.gov/pubmed/25232952 http://dx.doi.org/10.1371/journal.pcbi.1003837 |