Allele-Specific Network Reveals Combinatorial Interaction That Transcends Small Effects in Psoriasis GWAS

Hundreds of genetic markers have shown associations with various complex diseases, yet the “missing heritability” remains alarmingly elusive. Combinatorial interactions may account for a substantial portion of this missing heritability, but their discoveries have been impeded by computational comple...

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Detalles Bibliográficos
Autores principales: Climer, Sharlee, Templeton, Alan R., Zhang, Weixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168982/
https://www.ncbi.nlm.nih.gov/pubmed/25233071
http://dx.doi.org/10.1371/journal.pcbi.1003766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168982/
https://www.ncbi.nlm.nih.gov/pubmed/25233071
http://dx.doi.org/10.1371/journal.pcbi.1003766

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