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Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells

Although DNA modification is adaptive to extrinsic demands, little is known about epigenetic alterations associated with adipose differentiation and reprogramming. We systematically characterized the global trends of our methylome and transcriptome data with reported PPARγ cistrome data. Our analysi...

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Detalles Bibliográficos
Autores principales: Takada, Hitomi, Saito, Yutaka, Mituyama, Toutai, Wei, Zong, Yoshihara, Eiji, Jacinto, Sandra, Downes, Michael, Evans, Ronald M, Kida, Yasuyuki S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169011/
https://www.ncbi.nlm.nih.gov/pubmed/25093444
http://dx.doi.org/10.4161/epi.29856