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Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells
Although DNA modification is adaptive to extrinsic demands, little is known about epigenetic alterations associated with adipose differentiation and reprogramming. We systematically characterized the global trends of our methylome and transcriptome data with reported PPARγ cistrome data. Our analysi...
Autores principales: | Takada, Hitomi, Saito, Yutaka, Mituyama, Toutai, Wei, Zong, Yoshihara, Eiji, Jacinto, Sandra, Downes, Michael, Evans, Ronald M, Kida, Yasuyuki S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169011/ https://www.ncbi.nlm.nih.gov/pubmed/25093444 http://dx.doi.org/10.4161/epi.29856 |
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