Human factors and pathways essential for mediating epigenetic gene silencing

Cellular identity in both normal and disease processes is determined by programmed epigenetic activation or silencing of specific gene subsets. Here, we have used human cells harboring epigenetically silent GFP-reporter genes to perform a genome-wide siRNA knockdown screen for the identification of...

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Detalles Bibliográficos
Autores principales: Poleshko, Andrey, Kossenkov, Andrew V, Shalginskikh, Natalia, Pecherskaya, Anna, Einarson, Margret B, Marie Skalka, Anna, Katz, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169020/
https://www.ncbi.nlm.nih.gov/pubmed/25147916
http://dx.doi.org/10.4161/epi.32088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169020/
https://www.ncbi.nlm.nih.gov/pubmed/25147916
http://dx.doi.org/10.4161/epi.32088

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