Novel Nitrobenzazolo[3,2-a]quinolinium Salts Induce Cell Death through a Mechanism Involving DNA Damage, Cell Cycle Changes, and Mitochondrial Permeabilization

This study reports the capacity of three nitro substituted benzazolo[3,2-a]quinolinium salts NBQs: NBQ 95 (NSC-763304), NBQ 38 (NSC 763305), and NBQ 97 (NSC-763306) as potential antitumor agents. NBQ’s are unnatural alkaloids possessing a positive charge that could facilitate interaction with cell o...

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Detalles Bibliográficos
Autores principales: Vélez, Christian, Cox, Osvaldo, Rosado-Berrios, Carlos A., Molina, Dennise, Arroyo, Luz, Carro, Sujey, Filikov, Anton, Kumar, Vineet, Malhotra, Sanjay V., Cordero, Marisol, Zayas, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169051/
https://www.ncbi.nlm.nih.gov/pubmed/25243104
http://dx.doi.org/10.4236/ojapo.2013.22002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169051/
https://www.ncbi.nlm.nih.gov/pubmed/25243104
http://dx.doi.org/10.4236/ojapo.2013.22002

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