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VISPA: a computational pipeline for the identification and analysis of genomic vector integration sites
The analysis of the genomic distribution of viral vector genomic integration sites is a key step in hematopoietic stem cell-based gene therapy applications, allowing to assess both the safety and the efficacy of the treatment and to study the basic aspects of hematopoiesis and stem cell biology. Ide...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169225/ https://www.ncbi.nlm.nih.gov/pubmed/25342980 http://dx.doi.org/10.1186/s13073-014-0067-5 |