Cargando…

Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster

Forkhead box O (FoxO) transcription factors (TFs) are key drivers of complex transcriptional programmes that determine animal lifespan. FoxOs regulate a number of other TFs, but how these TFs in turn might mediate the anti-ageing programmes orchestrated by FoxOs in vivo is unclear. Here, we identify...

Descripción completa

Detalles Bibliográficos
Autores principales: Alic, Nazif, Giannakou, Maria E., Papatheodorou, Irene, Hoddinott, Matthew P., Andrews, T. Daniel, Bolukbasi, Ekin, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169242/
https://www.ncbi.nlm.nih.gov/pubmed/25232726
http://dx.doi.org/10.1371/journal.pgen.1004619