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Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster
Forkhead box O (FoxO) transcription factors (TFs) are key drivers of complex transcriptional programmes that determine animal lifespan. FoxOs regulate a number of other TFs, but how these TFs in turn might mediate the anti-ageing programmes orchestrated by FoxOs in vivo is unclear. Here, we identify...
Autores principales: | Alic, Nazif, Giannakou, Maria E., Papatheodorou, Irene, Hoddinott, Matthew P., Andrews, T. Daniel, Bolukbasi, Ekin, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169242/ https://www.ncbi.nlm.nih.gov/pubmed/25232726 http://dx.doi.org/10.1371/journal.pgen.1004619 |
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