Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...

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Detalles Bibliográficos
Autores principales: Banovich, Nicholas E., Lan, Xun, McVicker, Graham, van de Geijn, Bryce, Degner, Jacob F., Blischak, John D., Roux, Julien, Pritchard, Jonathan K., Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169251/
https://www.ncbi.nlm.nih.gov/pubmed/25233095
http://dx.doi.org/10.1371/journal.pgen.1004663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169251/
https://www.ncbi.nlm.nih.gov/pubmed/25233095
http://dx.doi.org/10.1371/journal.pgen.1004663

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