Cargando…

Application of a synthetic human proteome to autoantigen discovery through PhIP-Seq

In this study, we improve on current autoantigen discovery approaches by creating a synthetic representation of the complete human proteome, the T7 “peptidome” phage display library (T7-Pep), and use it to profile the autoantibody repertoires of individual patients. We provide methods for 1) designi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Larman, H. Benjamin, Zhao, Zhenming, Laserson, Uri, Li, Mamie Z., Ciccia, Alberto, Gakidis, M. Angelica Martinez, Church, George M., Kesari, Santosh, LeProust, Emily M., Solimini, Nicole L., Elledge, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169279/ https://www.ncbi.nlm.nih.gov/pubmed/21602805 http://dx.doi.org/10.1038/nbt.1856

Ejemplares similares

PhIP-Seq Reveals Autoantibodies for Ubiquitously Expressed Antigens in Viral Myocarditis
por: Rasquinha, Mahima T., et al.
Publicado: (2022)

Detecting and quantifying antibody reactivity in PhIP-Seq data with BEER
por: Chen, Athena, et al.
Publicado: (2022)

Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq
por: Vazquez, Sara E, et al.
Publicado: (2020)

phippery: a software suite for PhIP-Seq data analysis
por: Galloway, Jared G, et al.
Publicado: (2023)

Protein interaction mapping with ribosome-displayed using PLATO ORF libraries
por: Zhu, Jian, et al.
Publicado: (2013)

Phage ImmunoPrecipitation Sequencing (PhIP-Seq): The Promise of High Throughput Serology
por: Tiu, Charles Kevin, et al.
Publicado: (2022)

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq
por: Vazquez, Sara E, et al.
Publicado: (2022)

Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
por: Vazquez, Sara E, et al.
Publicado: (2022)

Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights
por: Klepper, Arielle, et al.
Publicado: (2023)

New discovery of high-affinity SARS-CoV-2 spike S2 protein binding peptide selected by PhIP-Seq
por: Chen, Mengyuan, et al.
Publicado: (2022)

Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli
por: Canene-Adams, Kirstie, et al.
Publicado: (2013)

Correction: Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli
por: Canene-Adams, Kirstie, et al.
Publicado: (2014)

Correction: Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli
por: Canene-Adams, Kirstie, et al.
Publicado: (2014)

DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP
por: Mimmler, Maximilian, et al.
Publicado: (2016)

P53-mediated in vitro inhibition of PhIP-induced oxidative damage by myricetin bulk and nano forms in healthy lymphocytes
por: Akhtar, Shabana, et al.
Publicado: (2021)

Combined Genotoxic Effects of a Polycyclic Aromatic Hydrocarbon (B(a)P) and an Heterocyclic Amine (PhIP) in Relation to Colorectal Carcinogenesis
por: Jamin, Emilien L., et al.
Publicado: (2013)

Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice
por: Machida, Yukino, et al.
Publicado: (2021)

Hydrogenative-PHIP polarized metabolites for biological studies
por: Reineri, Francesca, et al.
Publicado: (2021)

Development and Distribution of 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]‐pyridine (PhIP)‐induced Aberrant Crypt Foci in the Rat Large Intestine
por: Tsukamoto, Tetsuya, et al.
Publicado: (1999)

Ex vivo/in vitro protective effect of myricetin bulk and nano-forms on PhIP-induced DNA damage in lymphocytes from healthy individuals and pre-cancerous MGUS patients
por: Akhtar, Shabana, et al.
Publicado: (2020)

Clinical and genetic characterization of individuals with predicted deleterious PHIP variants
por: Craddock, Kirsten E., et al.
Publicado: (2019)

circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression
por: Su, Wen, et al.
Publicado: (2020)

Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer
por: Malik, Durr-e-shahwar, et al.
Publicado: (2018)

Metabolism of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in isolated liver cells from guinea pig, hamster, mouse, and rat.
por: Alexander, J, et al.
Publicado: (1994)

2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
por: Rogers, Lora J., et al.
Publicado: (2016)

Chemoprevention by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, of 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP)‐induced Mammary Gland Carcinogenesis in Rats
por: Nakatsugi, Seiichi, et al.
Publicado: (2000)

Isorhamnetin and Hispidulin from Tamarix ramosissima Inhibit 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP) Formation by Trapping Phenylacetaldehyde as a Key Mechanism
por: Ren, Xiaopu, et al.
Publicado: (2020)

Prognostic Impact of PHIP Copy Number in Melanoma: Linkage to Ulceration
por: Bezrookove, Vladimir, et al.
Publicado: (2013)

Real-Time Pyruvate Chemical Conversion Monitoring Enabled by PHIP
por: Stevanato, Gabriele, et al.
Publicado: (2023)

A Scalable Gene Synthesis Platform Using High-Fidelity DNA Microchips
por: Kosuri, Sriram, et al.
Publicado: (2010)

Retraction Notice to: circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression
por: Su, Wen, et al.
Publicado: (2021)

HyperChIP: identification of hypervariable signals across ChIP-seq or ATAC-seq samples
por: Chen, Haojie, et al.
Publicado: (2022)

PHIP-associated Chung-Jansen syndrome: Report of 23 new individuals
por: Kampmeier, Antje, et al.
Publicado: (2023)

Determination of hydrogen exchange and relaxation parameters in PHIP complexes at micromolar concentrations
por: Sellies, Lisanne, et al.
Publicado: (2021)

SeqAcademy: an educational pipeline for RNA-Seq and ChIP-Seq analysis
por: Ather, Syed Hussain, et al.
Publicado: (2020)

Effect of Different Amino Acids and Heating Conditions on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and Its Kinetics Formation Using Chemical Model System
por: Ishak, Ainaatul Asmaa, et al.
Publicado: (2019)

6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential
por: Yeh, I-Jeng, et al.
Publicado: (2019)

ChIP-PED enhances the analysis of ChIP-seq and ChIP-chip data
por: Wu, George, et al.
Publicado: (2013)

Immunogenicity of autoantigens
por: Backes, Christina, et al.
Publicado: (2011)

ChIP-Enrich: gene set enrichment testing for ChIP-seq data
por: Welch, Ryan P., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_cl69beoa6gcb2hu4kd0jm9vdql