Constant replenishment from circulating monocytes maintains the macrophage pool in adult intestine

The paradigm that resident macrophages in steady-state tissues are derived from embryonic precursors has never been investigated in the intestine, which contains the largest pool of macrophages. Using fate mapping models and monocytopenic mice, together with bone marrow chimeric and parabiotic model...

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Detalles Bibliográficos
Autores principales: Bain, Calum C., Bravo-Blas, Alberto, Scott, Charlotte L., Perdiguero, Elisa Gomez, Geissmann, Frederic, Henri, Sandrine, Malissen, Bernard, Osborne, Lisa C., Artis, David, Mowat, Allan McI.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169290/
https://www.ncbi.nlm.nih.gov/pubmed/25151491
http://dx.doi.org/10.1038/ni.2967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169290/
https://www.ncbi.nlm.nih.gov/pubmed/25151491
http://dx.doi.org/10.1038/ni.2967

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