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Constant replenishment from circulating monocytes maintains the macrophage pool in adult intestine
The paradigm that resident macrophages in steady-state tissues are derived from embryonic precursors has never been investigated in the intestine, which contains the largest pool of macrophages. Using fate mapping models and monocytopenic mice, together with bone marrow chimeric and parabiotic model...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169290/ https://www.ncbi.nlm.nih.gov/pubmed/25151491 http://dx.doi.org/10.1038/ni.2967 |